SuperSmart's S-Acetyl Glutathione is a food supplement that provides reduced glutathione in S-acetylated form, designed to improve its stability and bioavailability compared to conventional glutathione. This form helps maintain cellular oxidative balance and is suitable as antioxidant support.
This innovative form allows glutathione to escape oxidation in the gut, maximizing its bioavailability and effective entry into the cells of the human body.
Glutathione is a molecule naturally synthesized in the cells of the human body. It is composed of three peptides: glutamic acid, cysteine, and glycine. Its production decreases with age, and in some cases, it is insufficient to properly defend the body.
Properties and benefits
Once in the intestine, glutathione molecules are surrounded by intestinal enzymes, gamma-glutamyl transpeptidases, which break them down into relatively useless compounds. However, some molecules escape these attacks: they cross the intestinal barrier even before being oxidized by the enzymes, thus reaching the bloodstream in a fully functional state. Unfortunately, the proportion of these molecules is low, so large amounts of glutathione must be ingested for supplementation to be truly effective.
One of the relevant strategies for benefiting from glutathione involves attaching it to an acetyl group to prevent its oxidation by enzymes. The acetylated glutathione then crosses the intestinal barrier, penetrates the cells, and subsequently loses its acetyl group under the effect of cytoplasmic thioesterases.
It is one of the most effective solutions to increase serum glutathione levels, via the perlingual route (perlingual glutathione reaches the bloodstream without passing through the intestine, and therefore without crossing the gamma-glutamyl-transpeptidase pathway).
